Abstract
IntroductionRecent reports suggest that thromboembolic complications are associated with Pipeline embolization device (PED) placement cluster in P2Y12 hyporesponders.ObjectiveTo evaluate the role of P2Y12 hyporesponse in PED placement by retrospectively reviewing...
Highlights
Recent reports suggest that thromboembolic complications are associated with Pipeline embolization device (PED) placement cluster in P2Y12 hyporesponders
In this retrospective cohort study of 52 Plavix hyporesponders with P2Y12 reaction unit (PRU)>200 undergoing PED placement, 48 procedures (92%) were completed successfully without complications and there was a low rate of thromboembolic complications (4%)
The cases included here represent a cross-section of anterior circulation PED procedures from this institution and are not limited to proximal internal carotid artery aneurysms, which are known to have a lower complication rate The cases presented include patients with technically challenging anterior cerebral artery (ACA) aneurysms, patients with adjunctive coiling, and giant aneurysms, including, for instance, a 70-year-old woman who underwent uncomplicated PED placement with adjunctive coiling of a 26 mm ophthalmic aneurysm with a preprocedural P2Y12 of 252
Summary
Recent reports suggest that thromboembolic complications are associated with Pipeline embolization device (PED) placement cluster in P2Y12 hyporesponders. In this study we sought to evaluate the role of P2Y12 hyporesponse in PED placement by retrospectively reviewing a single-center series of patients
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