P.2.e.007 Medication prescription pattern for outpatients with bipolar disorder; focusing on atypical antipsychotics

Abstract

Medication Prescription Pattern for Outpatients with Bipolar Disorder: Focusing on Atypical Antipsychotics Young Sup Woo, MD, Won-Myong Bahk MD, Kyung Joon Min MD, Kyooseob Ha MD, Duk-In Jon MD, Hyun Sang Cho MD and Bo-Hyun Yoon MD Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Department of Neuropsychiatry, College of Medicine, Chung-Ang University, Seoul, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Department of Psychiatry, College of Medicine, Hallym University, Anyang, Department of Psychiatry, Yonsei University College of Medicine, Seoul, Naju National Hospital, Naju, Korea Objective:In the last decade, a number of pharmacological agents have shown efficacy in the treatment of bipolar disorder. Traditionally, lithium has been considered as the treatment of choice of bipolar disorder. However, more recently, atypical antipsychotics and newly developed anticonvulsants have become increasingly popular alternatives to lithium. This study examined the prescribing patterns for medications to treat bipolar disorder in office-based psychiatric practice. Methods:The data for the present study were collected by using structured record form from November 2005 to December 2005. Psychotropic medications were grouped into six categories; atypical antipsychotics, typical antipsychotics, lithium, anticonvulsants, antidepressants, and minor tranquilizers. Prescription data of 700 cases with a diagnosis of bipolar disorder according to DSM-IV from 70 Korean psychiatrists were accessed. Severity, mood episode, psychiatric comorbidity and point of diagnosis related utilization rates were computed focusing on atypical antipsychotics. Results:In 695 patients who were prescribed major psychotropic medications, atypical antipsychotics were prescribed in 62.4% of subjects, anticonvulsants in 58.7%, lithium in 47.8%, antidepressants in 17.6%, and typical antipsychotics in 15.5% of subjects. About seventeen percent of subjects were treated with the monotherapy. Atypical antipsychotics prescription was favored in subjects with manic and mixed episodes or severe episode. Lithium and typical antipsychotics prescription were less frequent in depressive subjects than subjects with other mood episodes. Prescription of atypical antipsychotics 접수일자:2006년 10월 2일 / 심사완료:2006년 11월 2일 본 논문의 요지는 2006년도 대한우울·조울병학회와 대한신경정신의학회 추계학술대회에서 발표되었음. 교신저자:박원명, 150-713 서울 영등포구 여의도동 62 가톨릭대학교 의과대학 정신과학교실 전화:(02) 3779-1250, 1735·전송:(02) 780-6577 E-mail:wmbahk@catholic.ac.kr