Abstract

Early diagnosis and management of TB is critical to reduce TB transmission in communities and health care facilities. In developing countries, TB diagnosis is largely based on smear microscopy of sputum samples. Nucleic acid amplification tests (NAATs) have greatly facilitated TB testing by lowering the turnaround time to a day or less from two or more weeks for a culture result.

Highlights

  • Diagnosis and management of TB is critical to reduce TB transmission in communities and health care facilities

  • Our aim is to evaluate the diagnostic performance of the Xpert MTB/RIF and BD ProbTec Strand Displacement Amplification assays on smear-positive and smear-negative patient specimens submitted to King Abduaziz Medical City laboratory, in Riyadh, Saudi Arabia from July to Mid Nov 2012, the study still ongoing to collect more data

  • Eight samples were positive by ProbTec alone and one sample positive by Xpert alone

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Summary

Introduction

Diagnosis and management of TB is critical to reduce TB transmission in communities and health care facilities. Nucleic acid amplification tests (NAATs) have greatly facilitated TB testing by lowering the turnaround time to a day or less from two or more weeks for a culture result

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