P275 SUBCHONDRAL BONE MINERAL DENSITY CHANGES IN CLINICAL AND RADIOGRAPHIC OSTEOARTHRITIS OF THE KNEE: THE VIDEO STUDY

Abstract

However, since ThCtAB in the cMF and MT are correlated with one another, regression analyses performed with both MT and cMF revealed that ThCtAB variation accounts for 54% of the variation in mJSW. Conclusions: Results from this study support the notion that joint space is indeed a surrogate measure of cartilage thickness. More importantly, however, these results provide insight into the proportion of variation in mJSW which can be accounted for by the variation in ThCtAB of the cMF and MT. While approximately half of the variation in mJSW is accounted for by variation in ThCtAB of cMF (51.3%) and approximately a third (35.0%) by MT, together ThCtAB accounts for roughly 54% of mJSW variation. Although it is not possible to discern if the remaining variation comes from other tissues or the fact that cartilage thickness values here represent mean thickness over the entire cartilage plate versus a one-dimensional measurement at one location, this is the first study to investiage the relative contributions of medial femoral and tibial cartilage thickness to mJSW in a group of individuals with knee OA.