P262. Emotion Generation and Regulation Volumes Associated With Depression and Anxiety Dimensional Symptoms

Abstract

Anxiety and depression are highly comorbid, yet existing research examines these disorders as distinct categories. This approach has shown opposite neuroanatomical findings; anxiety with volumetric increases in threat, reward, and emotion regulation-related regions and depression has been associated with volumetric reductions in these same regions. A dimensional model of psychopathology may provide insight into mechanisms underlying comorbidity and improve specificity and sensitivity of structural abnormalities.