Abstract
The p-glycoprotein efflux pump, encoded by the ABCB1 gene, has been shown to alter concentrations of various antidepressants in the brain. In this study, we investigated the association between selected ABCB1 single nucleotide polymorphisms (SNPs) and antidepressant treatment outcomes, including new and unpublished data from the Canadian Biomarker and Integration Network for Depression (CAN-BIND-1) cohort.
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