P250 Simultaneous recording of cervical and ocular vestibular-evoked myogenic potentials

Abstract

Objective To increase clinical application by reducing the testing time for recording vestibular-evoked myogenic potentials (VEMPs), we evaluated whether a simultaneous recording of ocular and cervical VEMPs after monaural and binaural stimulation can be achieved without a loss in diagnostic sensitivity and specificity. Methods Using randomized cross-over trials, 40 healthy subjects (HS) and 20 patients with acute vestibular neuritis underwent simultaneous recording of ocular and cervical VEMPs on each side during monaural stimulation, bilateral simultaneous recording of ocular VEMPs and cervical VEMPs during binaural stimulation, and conventional sequential recording of ocular and cervical VEMPs on each side using air-conducted sound (500 Hz, 5 ms tone-burst). We compared the time required to test and VEMP parameters among the study conditions. Clinical trial registration: NCT03049683. Results Either simultaneous recording during monaural and binaural stimulation effectively reduced the recording time by about 55% of that for conventional sequential recordings in both HS and patients groups. The simultaneous recording with monaural stimulation resulted in the latencies and thresholds of both VEMPs and amplitude of cervical VEMPs similar to those found during the conventional recordings in both groups, but larger oVEMP amplitude (156%) in HS. In contrast, compared to the conventional recording, simultaneous recording of each VEMP during binaural stimulation showed reduced amplitudes (31%) and increased thresholds for cervical VEMPs in both groups. Conclusion The results of simultaneous recording of cervical and ocular VEMPs during monaural stimulation were comparable to those obtained from the conventional recording while reducing the time to record both VEMPs on each side.