P25-5 Effective treatment of chemotherapy with EGFR Ab for an unresectable Lynch syndrome-associated small intestinal cancer

Abstract

Lynch syndrome is a hereditary disease caused by germline variants of the MMR gene, which impairs the MMR mechanism and results in MSI, leading to canceration. In recent years, it has been reported that ICI is effective for cancers in which the MMR mechanism is impaired, but there are few reports showing the effectiveness of cytotoxic and molecular-targeted agents.