P-232 - The comparison of fatigue between patients with diabetes melittus, psychiatric outpatients and general population in Greece

Abstract

Fatigue is of great clinical and investigational importance. It is a prevalent symptom in general population and a central symptom in many diseases, for example, cancer, ischaemic heart disease and depression. Besides, it's a side effect of many medical treatments. Fatigue has been shown to have a substantial impact on patients’ self care activities and, overall quality of life. To compare levels of the various aspects of fatigue in three different populations. To see if diagnosis is a significant predictor for fatigue. We conducted a survey in a random sample of 69 patients with diabetes Mellitus (DM), 114 psychiatric outpatients (PO) and 383 healthy adults (C), using the Multidimensional Fatigue Inventory (MFI-20). ANOVA test was used to reveille the statistical significance between the groups in all levels of fatigue. The control group had a significant difference to the PO and DM patients in physical fatigue (MD PO = -3.835 p < .001), (MD DM . = -2.745p< .001), in reduced activity (MD PO = -3.719 p < .001), (MD DM = -3.155 p < .001) and reduced motivation (MD PO = -3.569 p < .001), (MD DM = -2.349 p < .001). Psychiatric outpatients had a significant difference with DM patients and control in general fatigue (MD C = -4.135 p< .001), (MD DM . = -3.835 p < .001) and in mental fatigue (MD C = 4.638 p < .001), (MD DM . = 4.346 p < .001). Analysis shows that both psychiatric outpatients and patients with DM experience fatigue in all aspects of the measurement as expected, in a statistical significant level compared to the general population.