Abstract

Abstract Purpose: We developed a real-time virtual sonography (RVS) in which realtime ultrasound (US) images and reconstructive virtual US images of the same cross-section are synchronized based on US volume data obtained on the same monitor using magnetic position tracking system (US-RVS). The purpose of this study was to evaluate the accuracy of US-RVS to compare breast US images between different time phases. Materials and Methods: Between March 2010 and April 2011, US-RVS was performed in 108 consecutive patients with 112 target lesions for US (mean lesion size: 12 mm, 54 malignant and 58 benign). We used US-RVS system which consisted of sonography equipment, magnetic field generator, magnetic sensor, and workstation. To assess the accuracy of the US-RVS, we analyzed the sonographic re-identification rate of target lesions in different time phases. Results: Among the 112 target lesions, 105 (94%) lesions were re-identified by US-RVS. The remaining occult 7 (6%) lesions were included one DCIS and 6 fibrocystic changes in terms of the histological type, and one mass lesion and 6 nonmass like lesions in terms of morphological feature. US-RVS enabled us to precisely compare arbitrary cross-sections of US images in any direction between different time phases independent of the operator's skill. Conclusion: US-RVS, which requires no contrast medium and involves no radiation exposure, can be a useful modality for temporally tracking regions of interest using US. Citation Information: Cancer Res 2011;71(24 Suppl):Abstract nr P2-10-10.

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