P21.03: Advantage of three‐dimensional ultrasound in the differential diagnosis of benign and malignant breast tumors

Abstract

To explore the advantage of three-dimensional (3D) ultrasound in the differential diagnosis of benign and malignant breast tumors. 2D and the corresponding 3D ultrasound images of 120 breast solid lesions (69 malignant, 51 benign) in the 109 female patients were independently analyzed by five ultrasound doctors. Characteristics of seven 2D and ten 3D ultrasound were investigated. The advantage of 3D ultrasound in comparison with 2D ultrasound was analyzed using receiver operating characteristics (ROC) curve. All of the investigated ultrasound criteria were highly significant in characterizing breast lesions (P < 0.001). The detection rate of diagnostic characteristics of malignant lesions in 3D ultrasound was higher than those in 2D ultrasound. The sensitivity and specificity of the retraction phenomenon in the coronal plane of the 3D ultrasound to indicate malignant lesions were 56.8% and 93.7% respectively, and those of the irregular or spiculate margin contour to indicate malignant lesions were 92.2% and 51.8% respectively. The sensitivity and specificity of the complete interface echo to indicate benign lesions were 77.6% and 90.4% respectively. The area under ROC curve for 3D and 2D ultrasound were 0.9483 and 0.9086 respectively P < 0.05. 3D ultrasound can provide more evaluation characterization of the image. 3D ultrasound is more reliable than conventional 2D ultrasound in differential diagnosis of breast tumors. The diagnostic value of 3D ultrasound was better than 2D ultrasound.