P21.01: CA‐125 versus power Doppler as second step technique for predicting ovarian cancer in a large cohort of women with adnexal masses

Abstract

Multigravida A.P., 37 years old, was referred at 32 weeks of gestation to tertiary ultrasound unit because of BPD adequate for 38 gestational weeks. At the detailed scan absence of the right lens was diagnosed (images a, b), borderline ventriculomegaly and macrocephaly. The rest of morphology was normal. Normal male karyotype was found and TORCH screening was negative. MRI confirmed aphakia of the right eye (images c, d), as well as borderline ventriculomegaly, with no additional brain anomalies. A male infant was delivered by elective Caesarean section, 4370 gr/56 cm, AS 9/9, HC 39 cm. On the scan of the neonatal brain a diagnosis of incipient hydrocephalus was made. Ophthalmologist confirmed aphakia of the right eye, with a congenital glaucoma on the same eye. The child was closely monitored and at 20 days of age a spontaneous perforation of the right cornea developed, subsequent evisceration of the bulbus was performed. At the same time a congenital glaucoma of the left eye was diagnosed and trepanotrabeculectomia was performed. Conclusion: Ocular examination should be a part of a routine fetal scan. US and/or MRI visualisation of fetal eyes structures may be used to detect different orbital and ocular pathology. The morphological eye anomalies identified prenatally have to raise a high index of clinical suspicion of the associated functional disturbances, which can be postnatally corrected.