P205 Type I uterine cancer in US-born Asians versus immigrant Asians

Abstract

<h3>Background</h3> We investigated type I endometrioid uterine cancer in US-born Asians versus immigrant Asians. <h3>Methods</h3> Data was obtained from the National Cancer Institute from 2001 to 2009. Chi squared, t-test, and binomial regression methods were used for statistical analyses. <h3>Findings</h3> Of 4834 Asians with uterine cancer, 62% were born in the USA and 38% were immigrants. 2972 (61%) had type I uterine cancer (grade 1 or 2, endometrioid histology) and the remaining women had type II disease. Compared with patients with type II disease (grade 3, clear cell and serous histology), type I patients were younger (age 55 versus 59years; <i>p</i><0.01) and a higher proportion had lower-stage disease (90% versus 71%; <i>p</i><0.01). US-born Asians also had a significantly higher proportion of type I uterine cancers than immigrant Asians (65% versus 56%;<i>p</i><0.01). Among immigrant Asians, the proportion with type I cancers was lowest in Japanese followed by Chinese and Filipino women (48% versus 52% versus 58%; <i>p</i><0.01). The 5-year disease-specific survivals of US-born Asians versus immigrant Asians with type I cancer was 92% for both groups. Over three time periods (2001–2003, 2004–2006, and 2007–2009), there was an increase in type I uterine cancers among US-born Asians (61% to 65% to 68%; <i>p</i><0.01). <h3>Interpretation</h3> US-born Asians are more likely to be diagnosed with type I uterine cancer than immigrant Asians.