Abstract

Activity in the autonomic nervous system is often inferred from temporal changes in the heart beat interval, but all the derived measures presume a normal function of the sinus node. The T-wave of the ECG is a result of temporal differences in repolarisation between midmyocardial and epimyocardial cells primarily in the wall of the left ventricle and are thus dependent upon the activity of potassium channels at these sites. The potassium channels are under the influence of the autonomic nervous system and quantification of changes in T-wave amplitude (TWA) could offer an alternative to the study of autonomic activity towards the heart.

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