Abstract
Objective: Sporadic inclusion body myositis (sIBM) is the most common myopathy presenting over the age of 50 years. The diagnosis of sIBM is frequently delayed being initial errors common, as a consequent of the variation of clinical phenotype at presentation and frequent false negative results of initial muscle biopsy because of lack of rimmed vacuoles. For better diagnosis, we evaluate the clinical and radiological characteristics of Japanese patients with sIBM. Patients and methods: Thirteen patients (11 male and 2 female, being mean age of onset and diagnosis 58±8 years old and 65±8 years old, respectively) with sIBM based on muscle biopsy in the Department of Neurology, the University of Tsukuba Hospital over a 33-year period from 1976 to 2009 were included in this study.
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