Abstract
A 71-year-old man complaining of bilateral leg edema and general fatigue was admitted to the hospital and diagnosed as advanced sigmoid colon cancer with multiple liver and lung metastasis. 5-FU/Leucovorin/Oxaliplatin(FOLFOX)/Bevacizumab was started as a first-line therapy. In the second course of FOLFOX/Bevacizumab, just after finishing infusion of bevacizumab, he felt severe thrill with chill and got fever (maximum of 38.1 degree Celsius). Since the symptom was diagnosed as an infusion reaction induced by Bevacizumab, treatment with steroid and histamine antagonist was performed.
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