Abstract

Nivolumab, an immune checkpoint inhibitor, exerts anti-tumor effects against various types of malignant tumor, whereas all usual care should be taken to its related adverse events including immune-related adverse events (irAEs). Of these events, nivolumab-induced pneumonitis, which infrequently develops but sometimes results in a fatal outcome, requires an early detection and prompt response. The purpose of this study was to understand the pathogenesis of nivolumab-induced pneumonitis, leading to avoiding its onset and increase in severity.

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