Abstract
Convergent findings support reduced amygdala volume in adolescents and young adults with bipolar disorder (BD) and especially implicate the right amygdala. Most prior research assessed whole amygdala volume. However, amygdala nuclei have different connections and functions. Identifying affected nuclei might also differentiate BD from other disorders also associated with whole amygdala volume decreases. The lateral nucleus (LN) is implicated, as it performs functions disrupted in BD, including assigning salience to sensory stimuli and regulating emotion.
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