Abstract
Immune dysregulation, polyendocrinopathy, X-linked syndrome (IPEX) is a disorder caused by a mutation in FOXP3, a transcription factor essential for development and function of regulatory T cells (Tregs). While aggressive immunosuppression is imperative due to the early mortality seen in untreated patients, this also poses risks. Here we describe a 25-year-old IPEX patient with recalcitrant dermatitis and the search for optimal treatment.
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