Abstract

The use of local ablative therapy to treat NSCLC with oligometastatic disease (metastatic disease present in a limited number of sites) and oligoprogressive disease (disease progression in a limited number of sites) has been explored in multiple small prospective and retrospective series. Both Gomez et al 2016 and Iyengar et al 2017 have shown the benefit of radiation therapy as consolidative therapy for oligometastatic disease treated with chemotherapy or targeted therapy. For oligoprogressive disease, numerous retrospective studies indicate a benefit with the use of local ablative therapies in patients receiving targeted therapy.

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