P1806 Relation between carotid artery wave intensity compression wave and left ventricular dp/dt

Abstract

Abstract Background Invasive catheter-based studies demonstrated a correlation between left ventricular (LV) dP/dt, a well known index of contractility, and carotid artery wave intensity compression wave. It is possible to estimate LV dP/dt with ultrasound, evaluating the slope of continuous Doppler wave of mitral regurgitation in early systole. Wave intensity (WI) is achieved merging the echo-tracking of the common carotid artery with the simultaneous pulsed Doppler signal inside the vessel. The first peak (W1) represents the forward compression wave, reflecting theoretically LV contractile function. Nowadays data about the relationship between the two dP/dt methods are scarce. Purpose The aim of the study is to compare carotid artery WI and mitral regurgitation wave-derived LV dP/dt in a population of patients with ischemic and not ischemic heart failure. Methods We examined 31 consecutive patients with heart failure (7 females, 24 males, mean age 66.7 + 13.9 years, range 29-97 years, 21 ischemic, 10 not ischemic). All patients had at least a mild mitral regurgitation. Two subgroups were created according to the left ventricle ejection fraction values (LVEF ≤ 45% and LVEF > 45%, with 15 and 16 patients respectively). A simultaneous not-invasive brachial blood pressure was obtained. Results The W1 was significantly linearly correlated with the echocardiographic LV dP/dt value (r = 0.41, p 0.02). Both W1 and LV dP/dt correlated significantly with LV ejection fraction. Conclusions Carotid WI evaluation, and specifically its first peak W1, could be reinterpreted as an alternative method to estimate not invasively LV contractility performance. Larger studies are needed to evaluate the relative prognostic role of carotid artery W1 and LV dP/dt in clinical practice. Results LVEF ≤ 45 % (n = 15) LVEF > 45 % (n = 16) p value W1 6.19 +- 3.77 9.3 +- 3.43 0.02 dP/dT 789 +- 329 1244 +- 337 0.0007 Abstract P1806 Figure. Common Carotid Artery eTracking