P18-S Electrodiagnostic examination in Guillain–Barré Syndrome, a retrospective series of 32 patients

Abstract

Objectives To describe a retrospective series of 32 cases of Guillain-Barre Syndrome (GBS), with the intention to discuss timing and number of electrodiagnostic studies, electrodiagnostic classification subtypes and the presence of abnormal median/normal sural (AMNS) pattern. Methods Restrospective descriptive study, based on the review of the medical records and electrodiagnostic studies of 32 cases evaluated in our EDX/EMG laboratory, with a confirmed diagnosis of GBS, from 2010 to 2018. Results In our series of 32 patients, 14 were female (43.7%) and 18 were male (56.2%), they ranged from 22 to 87 years, with a median of 58.2 years (S.D: 17.1). Mean interval from disease onset to first nerve conduction study was 13.3 days (S.D.: 9.86). 15/32 (47%) had a second study, and only 2/32 (6%) had a third one. Using modified electrodiagnostic criteria by Rajabally et all (2015), 18/32 (56%) had Acute inflammatory demyelinating polyradiculoneuropathy (AIDP), 9/32 (28%) had axonal GBS, 3/32 (9%) had an equivocal form and 2/32(6%) had a normal study. 9/32 (28%) had an AMNS pattern (77% in cases of AIDP). Conclusion In concordance with other series, we consider that AMNS pattern is more frequent in AIDP subtypes of GBS. GBS subtypes according to newer electrodiagnostic criteria continue to demonstrate that AIDP subtypes are the most frequent GBS variant, with a 56% vs 28% axonal forms in our series.