P17.09: The frequency of chromosomal abnormalities among fetuses with increased nuchal translucency: an 8 year experience in one cytogenetic clinic

Abstract

USG markers found. Effectiveness was assessed based on 24 cases found due to 1st trimester calculations. Our 1st trimester screening sensitivity is 85.71%, false negative results-14.29%, false positive results-2.72%, specificity-98.32%, accuracy-98.19%. Found CA case/invasive procedure ratio is 1/1.3 in fact. In 2 cases (8.3%) from 24 cases of CA we found confined placental mosaicism. Conclusions: 1) Personal risks assessment of CA according to FMF recommendations showed high accuracy; 2) it resulted in significant decreasing of invasive procedures number; 3) to avoid possible diagnostic mistakes because of confined placental mosaicism amniocentesis should be preferred.