Abstract
Objective: Cost-effective, rapid tests are needed to allow for efficient use of colposcopic resources. Although HPV testing offers greater sensitivity than Pap smears, HPV testing alone has lower specificity for high-grade dysplasia and may increase colposcopy referral rates without increasing high-grade dysplasia detection rates. We investigated the feasibility of p16INK4a ELISA testing on fresh cervical smears as an adjunct to current screening modalities.
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