P1595NUTRITION AND INFLAMMATORY STATUS IN DIALYISIS PATIENTS WITH SUICIDAL IDEATION AND DEPRESSION

Abstract

Abstract Background and Aims The main precursor of suicidal ideation is depression, which is the most common psychiatric disorder in dialysis patients. Studies have shown an association of depression with nutritional alterations and systemic inflammation; however, in patients with kidney disease there is no data about a possible relation between malnutrition, inflammation and suicidal ideation. Therefore, the aim of this study was to describe and compare the nutritional and inflammation statuses in dialysis patients with suicidal ideation and depression. Methods Cross sectional study; 36 dialysis patients >18 years old, any gender, who signed informed consent were included. Suicidal ideation was measured by one psychiatrist using the Beck Scale for Suicidal Ideation, and depression with the Beck Depression Inventory. A dietitian evaluated nutritional status by means of anthropometric and biochemical variables, and the Dialysis Malnutrition Score. Additionally, C-reactive protein and fibrinogen were measured. Results were classified as dichotomous variables for suicidal ideation (yes/no) and depression (no: normal-mild/ yes: moderate-severe). Results Prevalence of depression, suicidal ideation and malnutrition were 97%, 63% and 31%, respectively. Main results are shown in the table. Conclusions Patients with suicidal ideation and depression did not show significant differences in any of the assessed nutritional variables. However, patients with suicidal ideation and depression seemed to have higher concentrations of C-reactive protein and fibrinogen. The present study opens an opportunity for future research.