P156 Local recurrence and mortality at two year follow up correlated to margin discrepancies of oral SCC tumors

Abstract

gene expression of SP and non-SP cells. We measured the expression of ABC transporter genes by real-time RT-PCR. SP fractions expressed higher levels of most ABC transporter genes than non-SP fractions especially ABCB1, not ABCG2. We could detect about 3 times higher expression of ABCB1/MDR1 in SP fraction than in non-SP fraction. Conclusion: The observations we described above indicated that cancer SP cell might have high survival potency, invasion ability, growth capability as well as drug resistance.