P150 Responsiveness of endoscopic indices in the evaluation of ulcerative colitis

Abstract

was 36.4±15.6 years. Disease duration was 7.0±6.4 years. The disease locations were 53 cases of pancolitis (73.6%), and 16 cases of left-sided colitis (27.2%). The clinical courses were 51 cases of relapse and remission (70.8%), 15 cases of chronically active colitis (20.8%), and 6 cases of fulminant or initial severe attack (8.4%). In terms of post-colectomy complication, there were 14 cases of intra-abdominal abscess, 13 cases of bowel obstruction, 8 cases of wound infection, 4 cases of bleeding and 2 cases of anastomotic leak (including overlapping cases). In emergency situations, 16 patients (22.2%) underwent colectomy due to toxic megacolon, severe bleeding, and perforation. Between emergency surgery (group A, n = 16) and elective surgery (group B, n = 56), there was no statistically significant difference in terms of the occurrence of complications [group A: 7/16 (43.6%), group B: 19/56 (33.9%)]. The analysis of risk factors for post-colectomy complications with univariate and multivariate studies was respectively performed in both groups. In group A, there was no significant factor. In group B, 7 years disease duration (OR: 6.65, 95%CI: 1.79 24.73), and >200mg/week preoperative prednisone use (OR: 9.80, 95%CI: 2.50 38.41) were statistically significant. Conclusions: The factors that correlated with an increased risk of post-colectomy complications in patients with UC were young onset ( 7 years), and a significant amount of preoperative prednisone use (>200mg/ week). To prevent such complications, we should treat these patients carefully.