P15 Prosthetic venous valves: short history and advancements from 2012 to 2020

Abstract

Abstract Introduction Venous diseases affect a majority of the population. It has both medical and cosmetic impacts on patients well-being. Patients have severe complications due to deep venous disease with few available therapies. A faulty venous valve is the origin of venous diseases, yet the treatment of such venous valves is invasive with a high recurrence rate. A prosthetic venous valve replacement is imminent and possibly provides better outcomes. Methods Articles addressing emerging implantable venous valve designs were examined. A systematic search resulted in thirty-five papers fitting the inclusion criteria. The focus was on the jugular vein and lower limbs veins and publication after 2012. Results Although no commercial model is in the market, many designs and models were studied especially in recent years. It was found that the composition of the valve determines its shape and the presence of inter/intra valve variability improved the approach toward a successful design. Three major models have been tested on animals awaiting further trials. Hence, a criterion for a successful prosthetic valve was formulated to avoid major complications and ensure the stability and durability of the valve. Conclusion The aim of the review is to shed light on the possible evolution in deep venous disease management especially since no ideal valve is available. If implemented, it can act as a treatment for early venous disease or to improve the quality of life if no alternative is available.