Abstract

Abstract Background In the MIRO trial, hybrid minimally invasive Ivor Lewis (IL) resulted in a lower incidence of intraoperative and postoperative major complications, specifically pulmonary complications, than open IL without compromising oncological resection criteria and 3 years survival results. However, only infracarenal and Siewert I oesogastric junction (OGJ) tumors were included. Whether hybrid approach for Siewert II OGJ tumours remains unknown with a potential risk of tumor spillage. The aim of this study was to compare hybrid and open IL for patients with Siewert II OGJ tumours. Materials and Methods Data from 83 patients who underwent surgery for Siewert II OGJ tumours in our institution were collected prospectively between 2011 and 2017. Overall, 53 patients were included in the hybrid group and 30 in the open group. The main outcome was radicality of resection (R0 / R1 margins and number of lymph nodes resected). Groups were compared in univariate and multivariate analysis with a propensity score-adjustment. Results After adjustment, the hybrid and open groups were comparable in terms of number of lymph nodes resection: OR=0.65 (0.25-1.66) and radicality of resection; (R0/R1): OR=0.93 (0.10-8.58) with similar long term overall (OS) and disease-free (DFS) survival (5-year OS: 68% vs. 58%, p=0.463; 5-year DFS: 56% vs. 42%, p=0. 323). There were significantly fewer pulmonary complications in the hybrid group: OR=0.38 (.14-0.95). Conclusion Hybrid IL for Siewert II OGJ tumors do not compromise oncological quality resection and long term OS and DFS and results in a lower incidence of pulmonary complications than open IL.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.