Abstract
The development of circuit therapeutics for PTSD and anxiety-related disorders requires understanding network interactions during threat processing. Amygdala (AMY) and anterior-insula (aINS) have been identified as regions for anxiety-related processes. Due to their deep location and rapid coordination of neural oscillations, intracranial electroencephalography (iEEG) may offer unique insights into the pathophysiology of anxiety states. Here, we use iEEG to investigate functional connectivity between AMY and aINS during threat processing.
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