Abstract
Characterizing the interaction between interoceptive signals of bodily states and neural responses during threat avoidance may uncover the sustained physiological arousal observed in PTSD and anxiety-related disorders. Prior studies have shown that the insula integrates bodily signals to determine emotional responses to salient experiences. We previously conducted an intracranial electroencephalography (iEEG) study in epilepsy patients showing amygdala, insula, and cingulate oscillatory synchronization during threat processing.
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