Abstract
Introduction Chronic sleep restriction results from a number of factors; medical condition and social demands, and has adverse effects on daytime function, such as cognitive function and driving performance. We demonstrated that the acute sleep restriction (time in bed Objectives We examined the chronic effect of insufficient sleep on cerebral blood flow and cognitive function. Methods Ten healthy adults (mean age 19.0 years, mean BMI 22.5 kg/m2) were enrolled in this study. All participants spent > or = 8 h/night in bed prior to study day (sufficient sleep), followed by Results The peak oxyHb during the word fluency task was significantly reduced after insufficient sleep 1 and 3 than that after sufficient sleep. The percentage of correct responses on CPT-IP and 2- back test after insufficient sleep 3 were lower than those after sufficient sleep, though there were no significant differences on those. WCST did not significantly differ among insufficient sleep 1 and 3 and sufficient sleep. Conclusions The chronic sleep restriction reduced cortical oxygenation response, and might result in cognitive performance impairment.
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