Abstract
Introduction: Breast Cancer (BC) is the most common female cancer (1). Initial histological grading of BC at core needle biopsy (CNB) is a strong determinant for treatment scheme and an independent prognostic factor (2). Accurate grading can be difficult secondary to tumour heterogeneity and inter/intra-observer subjectivity. Overall concordance of CNB and surgical excision for patients diagnosed by the National Health Service Breast Screening Programme (NHS BSP) should be 70% as stated by the Royal College of Pathologists. Grades one, two and three are expected to be seen at a ratio of 3:5:2 respectively (3). This study compares data from Leeds Teaching Hospitals Trust (LTHT) with these existing, strict Quality Assurance (QA) standards.
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