P126: Comparison of saline infusion sonography with diagnostic hysteroscopy for the evaluation of the uterine cavity in patients with abnormal uterine bleeding

Abstract

To evaluate the diagnostic accuracy of saline infusion sonography in the evaluation of the endometrium and uterine cavity in patients with abnormal uterine bleeding. The endometrium and uterine cavity of 100 patients complaining of abnormal uterine bleeding were evaluated by saline infusion sonography and findings were compared to office hysteroscopic evaluation of the same patients. Findings of endometrial hyperplasia, submucous myoma, endometrial polyps and atrophic endometrium were recorded independently and evaluation of the sensitivity and specificity and diagnostic significance for each of these findings was done. Dilatation and curettage was done in all cases to exclude or confirm endometrial hyperplasia and/or atypia. Both procedures were done in 100 patients. Findings of endometrial hyperplasia, endometrial polyps, submucous myoma, and atrophic endometrium were recorded. As regards endometrial hyperplasia, sensitivity was 94.74%, specificity was 93.6%, PPV was 90%, NPV was 96.5% and diagnostic accuracy 0.94. As regards endometrial polyp, sensitivity was 82.4, specificity was 95.2%, PPV was 77.8%, NPV was 96.4% and diagnostic accuracy 0.81. As regards submucous myoma, sensitivity was 94.3%, specificity was 97.6%, PPV was 88.3%, NPV was 98.8% and diagnostic accuracy 0.97. For all findings combined, sensitivity was 89.8%, specificity was 76.2%, PPV was 86.9%, NPV was 79.5% and diagnostic accuracy was 0.88. Saline infusion sonography is an accurate method to evaluate the endometrium and endometrial cavity in cases of abnormal uterine bleeding, compared with office diagnostic hysteroscopy.