Abstract
Introduction: The extent to which variations in body Fat Mass (FM) and Fat Free Mass (FFM) influence the risks of treatment related complication including chemotherapy toxicity is poorly characterised. Bioelectrical Impedance Analysis (BIA) can be used to estimate body composition and obtain impedance values at routine clinic appointments during neo/adjuvant chemotherapy for Early Breast Cancer (EBC). Differences in impedance measures of resistance, reactance and phase angle, and/or derived estimates of elevated FM index and low FFM index can be individually and/or jointly predictive of chemotherapy toxicity. Primary objective to determine if higher FMi is associated with increased grade 3 chemotherapy toxicity in women receiving neo/adjuvant chemotherapy for EBC.
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