Abstract
Introduction: Re-operation for positive pathological margins in breast conserving surgery remains high; researching intraoperative margin analysis (IMA) is identified as a priority by the recent ABS surgical gap analysis working group. High Wavenumber Raman Spectroscopy (HWNRS) is a method of vibrational spectroscopy that can rapidly assess changes in lipid, protein and water in biological specimens; changes that may differentiate between normal and cancerous breast tissue. We present a HWNRS system for future IMA.
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