P12.09: Analysis of the hemodynamics of fetal renal artery and fetal renal volume during the normal course of pregnancy

Abstract

Fetal kidney produces amniotic fluid and it is crucial for the fetal and development maturation. To evaluate fetal renal function by analyzing the hemodynamics of fetal renal artery and the renal volume, we have measured them in normal fetuses after 20 weeks of gestation using the color Doppler and 3D sonography. Hemodynamics analysis Maximum systolic: velocity (Vmax), mean velocity (Vmean), minimal velocity (Vmin), arterial cross sectional area (area), resistance index (RI) and pulsatility index (PI) of the fetal renal artery. Fetal renal volume: we can estimate that renal volume is lead to next following formula: renal volume (cm3) = < π> (abc)/6: r1 = a (cm), r2 = b (cm), r3 = c (cm). All hemodynamic indexes except RI and PI increased significantly with the course of pregnancy. Vmax, Vmean and area of the renal artery increased significantly from 21.80 ± 0.40 cm/s, 9.56 ± 0.17 cm/s and 6.78 ± 0.25 mm2 at 20–24 weeks to 41.59 ± 0.46, 20.15 ± 0.22 and 10.12 ± 0.19 at 37–40 weeks, respectively (P < 0.05). Renal Volume of the fetal kidney also increased significantly between the 20–24 weeks and the 37–40 weeks (1.375 ± 1.41 mm2 vs. 11.21 ± 1.63 mm2, P < 0.003).