Abstract
The aim of this study was to present our 4 cases of trisomy 18, with a congenital heart defect detected during the last 6 months.ResultsTwo complex congenital heart defects (CHD) with a very similar anatomy were found during a prenatal ultrasonographic examination – Double outlet right ventricle (DORV) with complete atrioventricular septal defect (AVSDC) – in the 20th and 38th week of gestation and in other two cases – in the 19th and 21st week of gestation – an isolated muscular ventricular septal defect (VSD) was proved. In All fetuses also noncardiac (central nervous, gastro‐intestinal and uropoetical) congenital malformations were present.ConclusionTrisomy 18 (Edwards sy) occurs approximately in 1:7000 live births. 95–100% of these newborns have some form of CHD. Because of a very poor prognosis a surgical correction is usually not considered. Left to their natural course, death occurs at the age of one hour to 18 months, the median life expectance is 5–48 days, according to the presence of severe CHD and associated anomalies.
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