P110/O18 Epigenetic changes by inhibition of DOT1L affect wnt signaling, proliferation and cell cycle in dermal fibroblasts, with no overall effect on collagen deposition in models of fibrosis

Abstract

Career situation of first and presenting authorStudent for a master or a PhD.IntroductionThe role of epigenetic factors in the pathophysiology of fibrosis, a hallmark of Systemic Sclerosis, is increasingly explored....