Abstract

Smoking is a well-known risk factor for the development of several diseases including cancer, but smoking cessation is a difficult problem even in patients who need hospitalization. The purpose of the study was to investigate the usefulness of inpatient smoking cessation consultation program. This study included patients who admitted to Chonnam National University Hwasun Hospital and were requested for Inpatient smoking cessation program by doctors or nurses from January to December 2018. We assessed the cessation rate at 4 weeks and 6 months, and evaluated clinical characteristics associated with success by electronic medical record system. Enrolled patients got counseling regularly for 6 months, and the success rate was confirmed by urine cotinine and exhaled carbon monoxide level. And we analyzed the differences of clinical characteristic and survival according to the registration status in lung cancer patients. A total of 571 patients were requested and 170 (29.8%) were enrolled to this program. One hundred thirty-eight (81.2%) patients had cancer and the majority was lung cancer (42.9%) followed by gastric cancer (11.2%). One hundred eleven (65.3%) patients were enrolled during their first admission. Only 6 (3.5%) patients took smoking cessation drugs in addition to counseling. The smoking cessation rate was 78.5% at 4 weeks and 39.2% at 6 months. The 4 week-cessation rate of cancer patients was higher than non-cancer (63.8% vs. 21.9%, p=0.000) and the rate of first admission group was higher than that of re-admission group, but it was not statically significant (67.0% vs. 47.8%, p=0.098). Also, the 6 month-cessation rate of cancer group was higher than non-cancer (45.7% vs. 3.8%, p=0.000) and the rate of first admission group was higher than that of re-admission, but not statically significant (49.3% vs. 29.4%, p=0.180). And 4 week-successful cessation group showed lower nicotine dependency than failed group (66.2% vs. 33.8%, p=0.046). In 155 of lung cancer patients, 73 (47.1%) were registered and 82 (52.9%) were refused. The registration rate of early stage group was higher than advanced stage group (83.3% vs. 34.4%, p=0.011). And the registration rate of operation group was higher than non-operation (64.5% vs. 42.7%, p=0.043) but the rate of chemotherapy group was lower than non-chemotherapy (41.2% vs. 58.5%, p=0.044). And the Progression free survival and Overall survival of registration group was better than refusal group, but not statically significant (p=0.199, p=0.215). Inpatient smoking cessation program was useful with high abstinence rate. Most patients could keep cessation without medication, so the diagnosis of cancer itself might be enough motivation. And smoking cessation after cancer diagnosis could improve survival rate in lung cancer.

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