Abstract
Background Infection of rhesus macaques with live-attenuated SIV strains provides the best known protection against challenge with pathogenic SIV. A cohort of 10 Indian rhesus macaques infected by Rev-independent live-attenuated SIV was monitored for up to 10 years. After the initial acute phase, virus replication was controlled and plasma viral loads were persistently below the threshold of the assay. None of the animals showed any signs of immune dysfunction.
Highlights
Infection of rhesus macaques with live-attenuated SIV strains provides the best known protection against challenge with pathogenic SIV
AIDS Vaccine 2009 Anna Laura Ross Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1471-2105-10-S12-info.pdf
A cohort of 10 Indian rhesus macaques infected by Rev-independent live-attenuated SIV was monitored for up to 10 years
Summary
Altered mucosal distribution of SIV-specific T cells in Rhesus macaques infected with the live-attenuated. Address: 1Center for Cancer Research, HRS, VB, NCI-Frederick, Frederick, USA, 2HRPS, VB, NCI-Frederick, Frederick, USA and 3California National Regional Primate Research Center, Davis, CA, USA. Published: 22 October 2009 Retrovirology 2009, 6(Suppl 3):P164 doi:10.1186/1742-4690-6-S3-P164. AIDS Vaccine 2009 Anna Laura Ross Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1471-2105-10-S12-info.pdf
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
