P1.06-045 Multiple Neoplasms Consist of Lung Cancer and Hematological Malignancies

Abstract

The lung cancer is a cancer of the most in Japan and first place in cause of death. Lung cancer (LC)is still poor prognosis disease that cure only in early clinical stage. We report that we reviewed 55 cases of multiple neoplasms with lung cancer and the hematological malignancies. We intended for multiple neoplasms 339 cases including hematological malignancy. We reviewed 55 multiple neoplasms including the lung cancer. All patients were followed up until death or until August 2016. Survival was measured from the diagnosis of multiple cancer to time of death or last contact. Definition of the multiple neoplasms in compliance with Warren & Gates. Also we determined the synchronous type and metachronous type in accordance with the definition of Moertel, so within less than 6 months was synchronous type, more than 6 months was metachronous type. All cases are 55 cases, consist of male 44 cases, female 11 cases, type of multiple neoplasms, synchronous type 14 cases, metachronous type 41 cases. Number of multiple neoplasms, double neoplasms 38 cases, triple neoplasms 14 cases, quadple neoplasms 3 cases. The median age was 71 years (range, 47-86 years) The counterpart of malignancies, MHL 26 cases, MDS 7 cases, AML 7 cases, HL 2 cases, MG 1 case, CLL 2 cases, CML 2 case, ALL 1 case, MGUS 3 cases. In double neoplasms, the median age of first diagnosis, 69 years, the second cancer were 71 years, about interval between lung cancer and hematological malignancies, lung cancer precedence case was 40M, hematological malignancy precedence case was 54M. The median overall survival was 24M. Diagnosis of LC within 5 years were 26 cases out of 41 cases. The important point is that 5 years are required for careful observation at the time of hematological malignancy diagnosis. We think that a prognosis is improved.