Abstract
BackgroundThe aim of this study was to assess whether changes of UV flow volume over time in late (third trimester) growth retarded fetuses (IUGR) are different than those in normal fetuses.MethodUmbilical morphometric characteristics and UV blood flow parameters of 15 women whose fetus was diagnosed to be IUGR without umbilical artery Doppler abnormality were compared to those of 30 women whose fetus was healthy. Gestational age and parity were used as matching criteria. Digital color Doppler velocity profile integration was used. For each patient, two scans were performed in a period of 3 weeks.ResultsThe umbilical cord area was significantly smaller in IUGR than in healthy fetuses at each examination (P < 0.05). The umbilical artery areas were not different between groups. The UV blood flow normalized for estimated fetal weight was lower in IUGR than in healthy fetuses 115 ± 41 vs. 145 ± 39, P < 0.05). The UV flow increase between two consecutive exams was significantly lower in IUGR than in healthy fetuses (P < 0.05).ConclusionThe umbilical cord area and the uv blood flow of IUGR were reduced in comparison to healthy fetuses. The normalized UV blood flow difference between IUGR and healthy fetuses increases with advancing gestation.
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