P1.03-057 Assessment of Lung Cancer Risk- Regional Respiratory Disease Screening Report in Jilin, China

Abstract

Both morbidity and mortality of lung cancer ranks first in China. According to the “2012 cancer registration report of China“, Northeast China is a high prevalence area of lung cancer, so early diagnosis of lung cancer is particularly important. Based on this, we made the regional survey in Changchun city. (1) To investigate the incidence of pulmonary nodules and lung cancer in Changchun city. (2)To provide the foundation of large data study on early screening of lung cancer and disease control. Carry out the investigation of the people over 50 years of age in 10 communities in Changchun of Jilin Province (A total of 1461 people), including questionnaire, pulmonary function tests and low-dose spiral CT examination. The disease assessment and patient management are based on “Diagnosis and treatment of pulmonary nodules in Chinese expert consensus.” The percentage of lung disease in the investigated population was 25.67%, and the constitution of the lung disease included: 30.67% of the lung nodules, 37.07% of chronic obstructive pulmonary disease, 18.67% of inflammation, 5.6% of the lung, 2.13% of pulmonary interstitial fibrosis, 2.13% of pleural effusion and 3.73% of other lung diseases. The number of pulmonary nodules was 115, accounting for 7.87% of the total number of screening, 89 cases of solitary nodules, 26 cases of multiple nodules. A total of 4 patients with lung cancer were confirmed by pathology, including 2 cases of adenocarcinoma, 1 case of squamous cell carcinoma and 1 case of mucinous carcinoma of the lung. All of the cancer cases were solitary nodules, and accounted for 3.48% of the total samples. Among them, 3 patients are male with a history of smoking, and 1 is female without any history of smoking. According to the nodule size, the diameters of nodule in 3 cases are greater than 8mm and 1 case is less than 4mm. According to the quality of nodules, 3 cases are solid and mixed nodules, and 1 case is ground-glass opacity. (1) Smoking is a risk factor for lung cancer. (2) Solid and mixed character nodules in pulmonary nodules and larger diameter nodules are more likely to develop into cancer, so they should be strengthened management. (3) Low-dose spiral CT is helpful for early diagnosis of lung cancer.