P101Doppler flow velocimetry in fetal and maternal circulation in relation to blood serum and amniotic fluid erythropoietin levels

Abstract

ObjectiveTo correlate arterial Doppler flow velocimetry with amniotic fluid and umbilical cord erythropoietin levels and umbilical cord gasometry.Material and methodsThe study compromised 80 pregnant woman who delivered in cesarean section without prior uterine contractions. The AB, PI and RI indexes of fetal umbilical, cerebral arteries as well as uterine arcuate arteries was assessed max. 24 h before delivery. Amniotic fluid was collected during the cesarean section before the uterine incision and umbilical cord blood was retrieved after the delivery, 1 min after the cord was clamped.ResultsThe correlation was found between umbilical arteries AB ratio and amniotic erythropoietin levels, fetal serum erythropoietin levels as well as umbilical artery pO2 and apgar score 5 min after delivery. The correlation was also found between fetal blood and amniotic fluid erythropoietin levels.ConclusionsDoppler flow velocimetry of umbilical artery reflects the fetal and newborn well being. Umbilical cord and amniotic fluid erythropoietin levels reflect fetal oxygenation. Erthropoietin levels may be checked in amniotic fluid beceause amniocentesis is related to lower incidence of complications in comparisone with cordocentesis.