P100. Differences in depression scores between women with a history of term hypertensive pregnancy disorders and women with a history of uncomplicated pregnancies

Abstract

Introduction Depression is among the leading causes of disability adjusted life years. For women in their fertile ages the occurrence of depression is of great impact for their selves and families. We analyzed the association between term hypertensive pregnancy disorders and depression scores. Methods Two to six years after pregnancy, women with a history of term preeclampsia or gestational hypertension were included in the hypertensive pregnancy cohort (HTP cohort) (n = 257). Controls were women who had an uncomplicated pregnancy (n = 83) (NTP cohort).The Edinburgh Postnatal Depression Scale (EPDS score) (Cox et al., 1987) was used to determine individual depression scores. Depression was defined as an EPDS score >12 or the use of antidepressants. Potential differences between groups were compared using the Student’s T test, the Chi-squared test ( X 2 test), or the Mann–Whitney U test when appropriate. We used logistic regression analyses to adjust for potential confounders. Results Women in the HTP cohort had higher depression scores than women in the NTP cohort (Table 1) and were more often depressed (OR 5.8 (1.4–24.6)). After correction for parity (adjusted OR 1.3 (0.8–2.0), BMI (adjusted OR 1.2 (1.1–1.2) and antihypertensive medication use (adjusted OR 1.1 (0.3–3.8), no significant differences were found in depression rates with an adjusted OR 4.2 (0.9–18.8). Conclusion More than three years postpartum women with a history of term hypertensive pregnancy disorders are more often depressed compared to women with a history of a normotensive pregnancy. Download : Download full-size image