P10.09: Assessment of 3D Power Doppler placental vascular indices in the second half of pregnancy

Abstract

Objective: Establish normative data for fetal liver volume (FLV) between 27 and 38 weeks gestation using three-dimensional ultrasonography (3DUS). Methods: This was a longitudinal prospective study involving 53 healthy participants. A total of 250 FLV measures were obtained; each pregnancy was evaluated 4 to 5 times during the study. The multiplanar method with 3.0 mm intervals was used. Polynomial regressions with adjustments using the determination coefficient (R ) were used to assess the correlation between FLV and gestational age (GA) and fetal parameters [biparietal diameter (BPD), head circumference (HC), abdominal circumference AC) and estimated fetal weight (EFW)]. The mean, standard deviation, median, minimum and maximum values were calculated for each gestational age. The intraclass correlation coefficient (ICC), BlandAltman graphs and Student’s paired t test (P) were used to determine inter and intraobserver reliability. Results: There was a high correlation between FLV and GA. The exponential regression was the model that best expressed the correlation between these variables: VHF = exp (0.114 × GA + 1.909), R = 0.815. The mean FLV went from 43.5 ± 7.6 cm (29.1–62.2 cm ) to 130.5 ± 20.1 cm (87.5–191.1 cm ). There was a high correlation between FLV and all fetal biometric parameters (BPD, HC, AC and EFW), all p . Conclusions: There was a high correlation between GA and biometric parameters. Reference limits were generated for FLV between 27 and 38 weeks. FLV is highly reproducible.