P1-51. Electrophysiological findings in patients with neuromyelitis optica

Abstract

The aim of this study was to report the electrophysiological findings in patients with neuromyelitis optica (NMO) differentiated from multiple sclerosis (MS). We diagnosed 17 patients with NMO based on the clinical symptoms, brain MRI, and aquaporin-4 antibody positivity. Those patients underwent visual evoked potential (VEP), auditory brainstem response (ABR), somatosensory evoked potential (SEP), and motor evoked potential (MEP) analyses. Forty-four point one percent of the patients presented abnormal VEP findings. All patients presented normal ABR findings. Abnomal findings were presented at rates of 8.8% in upper extremity SEP, 21.9% in lower extremity SEP, 13.6% in upper extremity MEP, and 36.4% in lower extremity. There were few abnormal subclinical findings in the electrophysiological findings. We found smaller percentage of abnormal findings in patients with NMO compared to patients with MS.