Abstract
that these changes in velocity and variability were not simply age-related. Conclusions: Cognitive impairment is characterized not only by memory loss, but also by functional impairment. Using quantitative gait analysis with dual task paradigms, we show that gait becomes slower and more variable as cognitive decline progresses. Particularly, gait cycle time variability increases during cognitive dual tasking compared to normal walking in thosewithMCI andmild AD. Early detection of these mobility impairments may be used as a tool to aid diagnosis of those in the earliest stages of cognitive impairment.
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