Abstract
Anti-Programmed death 1 (PD-1) antibody which enhances anti-tumor activity of cytotoxic T lymphocytes by blockade of PD-1/PD-L1 pathway has demonstrated improvement of survival in the patients with advanced non-small-cell lung cancer (NSCLC). PD-1 and its ligand PD-L1 is also known as key players in the formation of tumor microenvironment, closely related with inflammatory cytokines. Here, we retrospectively analyzed the potential of peripheral blood biomarkers for predicting outcome of anti-PD-1 antibody therapy.
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